Sarcosine

Catalog	BBC107971
CAS	107-97-1
Structure
Description	Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine. Sarcosine is an amino acid derivative that is naturally found in muscles and other body tissues. In the laboratory, it may be synthesized from chloroacetic acid and methylamine. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is sweet to the taste and dissolves in water. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications.Sarcosine is ubiquitous in biological materials and is present in such foods as egg yolks, turkey, ham, vegetables, legumes, etc.Sarcosine is formed from dietary intake of choline and from the metabolism of methionine, and is rapidly degraded to glycine, which, in addition to its importance as a constituent of protein, plays a significant role in various physiological processes as a prime metabolic source of components of living cells such as glutathione, creatine, purines and serine. The concentration of sarcosine in blood serum of normal human subjects is 1.4 ± 0.6 micromolar.
Synonyms	Methylglycine
IUPAC Name	2-(Methylamino)acetic acid
Molecular Weight	89.09
Molecular Formula	C3H7NO2
Canonical SMILES	CNCC(=O)O
InChI	InChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)
InChI Key	FSYKKLYZXJSNPZ-UHFFFAOYSA-N
Boiling Point	165.17 °C
Melting Point	208-212 °C(lit.)
Flash Point	>230 °F
Purity	98%
Density	1.1948 g/cm³
Appearance	Solid
Storage	Store below +30 °C
Active Content	95%
EC Number	203-538-6
pH	6.1
pKa	2.21(at 25 °C)
Refractive Index	1.4368
Solubility in Water	1480 g/L
Vapor Pressure	0.184mmHg at 25°C