Modified Nanocelluloses

Despite of its many beneficial features, the hydrophilicity of nanocellulose is posing a substantial challenge for the application of nanocellulose as reinforcing filler in conventional. Diverse surface-modification routes are being developed to improve the miscibility and interfacial compatibility of nanocellulose with hosting matrices and also to confer new functionalities^[1].

Modification Methods

Concerning the vastly hydrophilic nature of nanocellulose owing to the existence of OH groups on their surface, the surface modification of nanocellulose can be performed either via cellulose nanocrystal synthesis, physical adsorption or chemical modification. The summary of the most widespread modification methods is provided as below^[2]:

Modification Methods	Reaction Type	Exposed Functionality	Reagents
Via CNCs Synthesis	Hydrolysis	SO₃^-	H₂SO₄
		/	HCl
			HBr
			H₃PO₄
			Maleic acid
			Oxalic acid
			Tosylic acid
		Acetyl	CH₃COOH, HCl
Via Chemical Modification	Sulphonation	SO₃^-	H₂SO₄
	Oxidation	Dialdehyde	NaClO₄
	Oxidation	COOH	NaClO
	Carboxymethylation	Carboxymethl	Chloroacetic acid
	Amination	NH₂	(3-Aminopropyl) triethoxysilane
	Amination	NH₂	Fmoc-L-Leucine
	Epoxidation	Epoxide	Epichlorohydrin
	Carboxylation	COOH	1,2,3,4-Butanetetracarboxylic acid
	Azido functionalization	N₃	1-Azido-2,3-epoxypropane
	Azido functionalization	N₃	NaN₃
	Thiol-Alkene	SH	(3-Mercaptopropyl)trimethoxysilane
	Thiol-Alkene	Alkene	Vinyl trimethoxy silane
	Esterification	Tosyl	Tosyl chloride
	Esterification	Chlorotoxin	N-methyl pyrrolidinium hydrogensulfate

What We Offer

Sulfonated-CNC

Catalog: BBC131549
Diameter: 4-10nm
Length: 100-500nm
Surface groups: -SO3/-OH
Appearance: White paste
Applications: Pickering emulsion,
Drug sustained-release, Pharmaceutical excipients, Nanocarriers, Reinforced material, Liquid crystal material, etc.

Carboxylic-CNF

Catalog: BBC131550
Diameter: 4-10nm
Length: 1-3μm
Surface groups: -COONa/-OH
Appearance: White powder
Applications: Thickening agent, Thixotropic agent, Anti-precipitation agent, Dispersant, Biomedical materials, etc.

Carboxylic-CNC

Catalog: BBC131551
Diameter: 4-10nm
Length: 100-500nm
Surface groups: -COONa/-OH
Appearance: White to yellow powder
Applications: Thixotropic agent, Dispersant, Drug sustained-release, Pharmaceutical excipients, Nanocarriers, etc.

Alfa Chemistry is a professional supplier of modified nanocelluloses. In addition to the modified nanocelluloses above, we can offer custom synthesis according to customer's needs. For high quality products, professional technical service, use suggestion and latest industry news, please feel free to contact us.

References

Mehran Ghasemlou, Fugen Daver, Elena P.Ivanova, et al. Surface modifications of nanocellulose: From synthesis to high-performance nanocomposites. Progress in Polymer Science, Volume 119, August 2021, 101418.
Silvia Tortorella, Veronica Vetri Buratti, Mirko Maturi, et al. Surface-Modified Nanocellulose for Application in Biomedical Engineering and Nanomedicine: A Review. International Journal of Nanomedicine 2020:15 9909–9937.