Products

PDLLA (Poly D,L-lactide) Microspheres

PDLLA (Poly D,L-lactide) microspheres refer to microspheres made from poly-DL-lactic acid (PDLLA). PDLLA is an amorphous polymer composed of both L-lactic acid and D-lactic acid units, characterized by unique physical and chemical properties, as well as excellent biocompatibility and degradability. With these characteristics, PDLLA microspheres offer exceptional versatility in various applications such as drug delivery and aesthetic medicine. At present, it has been hailed as a new generation of medical regenerative materials, and the facial filler based PDLLA microspheres has been approved for market, showing great application potential.

Our Products

As a leading bio-based materials company, Alfa Chemistry is proud to present our PDLLA microspheres with unmatched quality and consistency to meet the highest standards of performance and sustainability.

Product Name: PDLLA (Poly D,L-lactide) Microspheres

Catalog: BBC-PLA302

Click Here to request a quote

Please note that this product is for scientific research purposes only and is not for other uses.

Product Details

Items	Typical Values
Appearance	White powder
Particle Size	20-60 μm
Intrinsic Viscosity	0.2-1.0 dL/g
Moisture Content	≤0.5%
Monomer Residue	≤0.5%
Solvent Residue (Dichloromethane and methanol)	Less than or equal to ICH limit value
Heavy Metal Residue (Pb)	≤10 μg/g
Sn Residue	≤100 μg/g
Specific Rotation	-10° to +10°

*Customized molecular weight and particle size are available according to customer requirements.

Key Features

Produced under stringent conditions to ensure minimal impurities.
Uniform particle size distribution to ensure consistent behavior and efficiency in end-use applications.
Customizable solution to meet specific application needs.
Available in a variety of sizes and formulations.

Storage

Store in sealed containers at room temperature or 4°C. Do not freeze.

Applications of PDLLA Microspheres

Aesthetic Medicine and Fillers: PDLLA microspheres have shown exceptional promise in aesthetic medicine. They can be used for shallow skin filling as well as deeper tissue and bone contouring, such as improving facial wrinkles, nasolabial folds, and other facial contours. Moreover, PDLLA microspheres possess a sponge-like porous structure, which results in a larger volume compared to PLLA microspheres of the same mass. This distinctive structure enhances the shaping effect significantly, and also promotes a more effective and controllable collagen regeneration process because collagen fibers can grow along the porous architecture within the microspheres.
Pharmaceuticals and Drug Delivery: PDLLA microspheres are extensively used as carriers for controlled drug release. Their ability to degrade into non-toxic byproducts ensures safe and predictable medication delivery, enhancing therapeutic outcomes. key applications include targeted cancer therapies, long-acting injectable formulations, and sustained release of vaccines and proteins.
Medical Devices and Others: The biocompatibility and tunable properties of PDLLA microspheres make them ideal for use in bioresorbable implants and scaffolds. Moreover, their role in tissue engineering and regenerative medicine is particularly noteworthy, supporting cell growth and facilitating healing.