L-Tryptophan

Catalog	BBC73223
CAS	73-22-3
Structure
Synonyms	L-Beta-3-indolylalanine
IUPAC Name	(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid
Molecular Weight	204.23
Molecular Formula	C11H12N2O2
Canonical SMILES	C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
InChI	InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChI Key	QIVBCDIJIAJPQS-VIFPVBQESA-N
Boiling Point	342.72 °C
Melting Point	289-290 °C(lit.)
Purity	99%
Density	1.34 g/cm³
Solubility	Slightly soluble in acetic acid, ethanol, insoluble in ethyl ether
Appearance	White to yellow-white powder
Application	Amino acids-type drug: It can be used in amino acid infusion, being often combined with iron and vitamins. Its co-administration with VB6 can improve depression and prevention/treatment of skin disease; as a sleep sedative, it can be combined with L-dopa for the treatment of Parkinson's disease. It is carcinogenic to experimental animals; it may cause adverse reactions including nausea, anorexia and asthmas. Avoid combination with monoamine oxidase inhibitors. Nutritional supplements: Tryptophan contained in egg white protein, fish meat, corn meal and other amino acids are limited; content in cereals such as rice is also low. It can be combined with lysine, methionine and threonine for enhanced amino acids. It can be supplemented to corn product at the content of 0.02% tryptophan and 0.1% lysine, being capable of significantly improving the protein potency.tryptophan is one of the 21 amino acids comprising a protein. Tryptophan is a component of the skin's natural moisturizing factors.
Storage	2-8 °C
Active Content	95%
EC Number	200-795-6
pH	5.5-7.0 (10g/l, H₂O, 20°C)
pKa	2.46(at 25 °C)
Refractive Index	-32 ° (C=1, H₂O)
Solubility in Water	11.4 g/L (25 ºC)
Vapor Pressure	2.1X10-9 mm Hg at 25 deg C (est);

Case Study

L-Tryptophan as A Kinetic Promoter of CO2 Hydrate Formation

Khandelwal, Himanshu, et al. Energy & Fuels, 2020, 35(1), 649-658.

Carbon dioxide (CO2) hydrates are a potential option for carbon dioxide capture and storage (CCS). L-tryptophan can be used as a kinetic accelerator for CO2 hydrate formation to increase the gas hydrate formation rate and process efficiency.
Performance evaluation of L-tryptophan accelerators
· The performance of the environmentally friendly accelerator L-tryptophan as a kinetic accelerator for CO2 hydrate formation was evaluated using a stirred tank reactor.
· The effect of L-tryptophan as a kinetic enhancer was studied using gas absorption measurements and front/top view visual observation.
· With the addition of only 300 ppm L-tryptophan, an average gas uptake of 114 v/v (78% water conversion to hydrate) was achieved at 273.65 K and 3.4 MPa, which is four times higher than without the accelerator.
· Experiments performed at 273.65 and 275.65 K showed shorter induction times and better gas absorption properties compared to 277.65 K.