| Application |
D-Mannose, a white crystalline powder, serves a vital role in glycosylation processes within human metabolism and cellular functions. This carbohydrate, structurally akin to glucose, is responsible for the N and O glycosylation of proteins, including those used in infant formulas and the T helper cell-derived cytokine interleukin-17A, which is crucial for cell signaling. Found naturally in fruits such as cranberries and peaches, D-mannose is particularly effective in preventing urinary tract infections (UTIs) by binding to the lectins on E. coli bacteria's fimbria, thereby facilitating their expulsion via urination. Additionally, D-mannose is used in treating carbohydrate-deficient glycoprotein syndrome and serves as a reference standard in monosaccharide analysis. Its slow absorption in the gastrointestinal tract and substantial excretion in the urine make it the most effective supplement for UTI prevention and treatment. Furthermore, D-mannose is utilized in selecting transfected sorghum seeds and as a culture medium supplement for human cell lines, underscoring its multifaceted applications in both health and research contexts. |
