Topotecan hydrochloride

Catalog	BBC119413546
CAS	119413-54-6
Structure
Description	Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities.
Synonyms	1,4-Di[4-(3-phenoxypropoxy)-2-butynyl]piperazine
IUPAC Name	(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
Molecular Weight	457.91
Molecular Formula	C23H24ClN3O5
Canonical SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl
InChI	InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
InChI Key	DGHHQBMTXTWTJV-BQAIUKQQSA-N
Melting Point	213-218 °C
Purity	98%
Appearance	Light-yellow powder
Solubility in Water	Slightly