Dihydrocapsaicin

Catalog	BBC19408845
CAS	19408-84-5
Structure
Description	Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat.
Synonyms	N-(4-Hydroxy-3-methoxybenzyl)
IUPAC Name	N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide
Molecular Weight	307.43
Molecular Formula	C18H29NO3
Canonical SMILES	CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
InChI	InChI=1S/C18H29NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h10-12,14,20H,4-9,13H2,1-3H3,(H,19,21)
InChI Key	XJQPQKLURWNAAH-UHFFFAOYSA-N
Boiling Point	497.4±35.0 °C
Melting Point	62-65 °C (lit.)
Purity	98%
Density	1.026±0.06 g/ml
Appearance	White powder
pKa	9.76±0.20