Coelonin

Catalog	BBC82344829
CAS	82344-82-9
Description	Coelonin is a dihydrophenanthrene with anti-inflammation activity. Coelonin inhibits LPS-induced PTEN phosphorylation. Coelonin inhibits NF-κB activation and p27Kip1 degradation by regulating the PI3K/AKT pathway negatively. Coelonin can inhibit IκBα phosphorylation and degradation and increases the expression of IκBα protein.
Synonyms	9,10-Dihydro-4-methoxy-2,7-phenanthrenediol
IUPAC Name	4-methoxy-9,10-dihydrophenanthrene-2,7-diol
Molecular Weight	242.27
Molecular Formula	C15H14O3
Canonical SMILES	COC1=CC(=CC2=C1C3=C(CC2)C=C(C=C3)O)O
InChI	InChI=1S/C15H14O3/c1-18-14-8-12(17)7-10-3-2-9-6-11(16)4-5-13(9)15(10)14/h4-8,16-17H,2-3H2,1H3
InChI Key	OPPGAHUCKDKQJR-UHFFFAOYSA-N
Purity	98%
Appearance	Solid